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The Cellular Prion Protein Controls Notch Signaling in Neural Stem/Progenitor Cells

Archive ouverte | Martin-Lannerée, Séverine | CCSD

International audience. The prion protein is infamous for its involvement in a group of neurodegenerative diseases known as Transmissible Spongiform Encephalopathies. In the longstanding quest to decipher the physio...

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Archive ouverte | Hirsch, Théo Z. | CCSD

International audience. Among the ever-growing number of self-replicating proteins involved in neurodegenerative diseases, the prion protein PrP remains the most infamous for its central role in transmissible spongi...

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Archive ouverte | Halliez, Sophie | CCSD

International audience. Although conversion of the cellular form of the prion protein (PrP(C)) into a misfolded isoform is the underlying cause of prion diseases, understanding PrP(C) physiological functions has rem...

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