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Rapid discovery of de novo deleterious mutations in cattle enhances the value of livestock as model species

Archive ouverte | Bourneuf, Emmanuelle | CCSD

In humans, the clinical and molecular characterization of sporadic syndromes is often hindered by the small number of patients and the difficulty in developing animal models for severe dominant conditions. Here we show that the av...

A 3.7 Mb deletion encompassing ZEB2 causes a novel polled and multisystemic syndrome in the progeny of a somatic mosaic bull

Archive ouverte | Capitan, Aurelien | CCSD

Polled and Multisystemic Syndrome (PMS) is a novel developmental disorder occurring in the progeny of a single bull. Its clinical spectrum includes polledness (complete agenesis of horns), facial dysmorphism, growth delay, chronic...

Identification of five novel mutations responsible for prenatal mortality in dairy cattle

Archive ouverte | Fritz, Sebastien | CCSD

Chantier qualité spécifique "Auteurs Externes" département de Génétique animale : uniquement liaison auteur au référentiel HR-Access. absent

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