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The translational value of the MPTP non-human primate model of Parkinsonism for deep brain stimulation research.

Archive ouverte | Tass, Peter A | CCSD

International audience. Deep brain stimulation (DBS) has been applied in more than 70000 patients worldwide during the last two decades. The main target is the subthalamic nucleus (STN) for the treatment of motor co...

Lack of additive role of ageing in nigrostriatal neurodegeneration triggered by α-synuclein overexpression

Archive ouverte | Bourdenx, Mathieu | CCSD

International audience

Lack of additive role of ageing in nigrostriatal neurodegeneration triggered by α-synuclein overexpression

Archive ouverte | Bourdenx, Mathieu | CCSD

International audience. INTRODUCTION:Parkinson's disease (PD) is a progressive neurodegenerative disorder characterized by the loss of dopaminergic neurons as well as the presence of proteinaceous inclusions named L...

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