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Cocaine-evoked negative symptoms require AMPA receptor trafficking in the lateral habenula

Archive ouverte | Meye, Frank, J | CCSD

International audience. Addictive substances mediate positive and negative states promoting persistent drug use. However, substrates for aversive effects of drugs remain elusive. We found that, in mouse lateral habe...

Synaptic and cellular profile of neurons in the lateral habenula.

Archive ouverte | Meye, Frank, J. | CCSD

International audience. The lateral habenula (LHb) is emerging as a crucial structure capable of conveying rewarding and aversive information. Recent evidence indicates that a rapid increase in the activity of LHb n...

Ventral Subiculum Stimulation Promotes Persistent Hyperactivity of Dopamine Neurons and Facilitates Behavioral Effects of Cocaine

Archive ouverte | Fois, Giulia r. | CCSD

International audience. Highlights d vSUB controls the phasic activity of VTA dopamine neurons d The BNST relays the excitatory drive from the vSUB to VTA dopamine neurons d vSUB stimulation promotes persistent hype...

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