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Detection of low-frequency HIV type 1 reverse transcriptase drug resistance mutations by ultradeep sequencing in naive HIV type 1-infected individuals.

Archive ouverte | Bellecave, Pantxika | CCSD

International audience. Genotypic resistance testing is recommended to evaluate the susceptibility of HIV to antiretroviral drugs. These tests are based on bulk population sequencing and thus consider only variants ...

Virological failure in cohorts of HIV-infected patients : contribution of ultra-deep sequencing and impact of persistent low-level viremia. Echecs virologiques au sein de cohortes hospitalières de patients adultes infectés par le VIH : apport de l'ultra-deep sequencing et étude des charges virales de faible niveau persistantes

Archive ouverte | Vandenhende, Marie-Anne | CCSD

The goal of antiretroviral therapy (ART) is to reach undetectable plasma HIV viral load in orderto reduce HIV-related morbidity and mortality.The presence of ART-resistant virus can compromise the efficiency of these treatments,re...

CMV plasma DNAemia and risk of cancer among HIV-infected patients: a case-control study nested in the ANRS CO3 Aquitaine Cohort, France, 2002-2007.

Archive ouverte | Bruyand, Mathias | CCSD

International audience. BACKGROUND: CMV reactivation, which enhances immune senescence, could be associated with a higher risk of cancer. OBJECTIVES: We compared the prevalence of positive CMV DNAemia in HIV-infecte...

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