Identification of the first human gyrovirus, a virus related to chicken anemia virus

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Sauvage, Virginie, V. | Cheval, Justine, J. | Foulongne, Vincent, V. | Ar Gouilh, Meriadeg, M. | Pariente, Kevin, K. | Manuguerra, Jean-Claude, J.-C. | Richardson, Jennifer | Dereure, Olivier, O. | Lecuit, Marc, M. | Burguiere, Ana, A. | Caro, Valerie, V. | Eloit, Marc

Edité par CCSD ; Microbiology Society -

We have identified in a skin swab sample from a healthy donor a new virus that we have named humangyrovirus (HGyV) because of its similarity to the chicken anemia virus (CAV), the only previously knownmember of the Gyrovirus genus. In particular, this virus encodes a homolog of the CAV apoptin, a protein that selectively induces apoptosis in cancer cells. By PCR screening, HGyV was found in 5 of 115 other nonlesionalskin specimens but in 0 of 92 bronchoalveolar lavages or nasopharyngeal aspirates and in 0 of 92 fecal samples.

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