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Differential role for CD277 as a co-regulator of the immune signal in T and NK cells

Archive ouverte | Messal, Nassima | CCSD

International audience. The human butyrophilin (BTN) 3 or CD277 molecules belong to the B7 family members and are expressed in various immune cells such as T and NK cells. Here, we show that CD277 triggering conside...

Differential role for CD277 as a co-regulator of the immune signal in T and NK cells.

Archive ouverte | Messal, Nassima | CCSD

International audience. The human butyrophilin (BTN) 3 or CD277 molecules belong to the B7 family members and are expressed in various immune cells such as T and NK cells. Here, we show that CD277 triggering conside...

PD-L2 is expressed on activated human T cells and regulates their function.

Archive ouverte | Messal, Nassima | CCSD

International audience. T-cell activation and proliferation are regulated by cosignaling adhesion molecules involved in positive or negative signals. Programmed death (PD)-1 is one of immune inhibitory molecules tha...

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