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Evidence for cardiomyocyte renewal in humans.

Archive ouverte | Bergmann, Olaf | CCSD

International audience. It has been difficult to establish whether we are limited to the heart muscle cells we are born with or if cardiomyocytes are generated also later in life. We have taken advantage of the inte...

Identification of cardiomyocyte nuclei and assessment of ploidy for the analysis of cell turnover.

Archive ouverte | Bergmann, Olaf | CCSD

International audience. Assays to quantify myocardial renewal rely on the accurate identification of cardiomyocyte nuclei. We previously (14)C birth dated human cardiomyocytes based on the nuclear localization of cT...

Dynamics of hippocampal neurogenesis in adult humans.

Archive ouverte | Spalding, Kirsty L | CCSD

International audience. Adult-born hippocampal neurons are important for cognitive plasticity in rodents. There is evidence for hippocampal neurogenesis in adult humans, although whether its extent is sufficient to ...

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