Evaluation of a 3D local multi-resolution algorithm for the correction of spatial volume effects in positron emission tomography

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Le Pogam, Adrien | Hatt, Mathieu | Descourt, Patrice | Boussion, Nicolas | Tsoumpas, Charalampos | Turkheimer, Federico E. | Prunier, Caroline | Baulieu, Jl | Guilloteau, Denis | Visvikis, Dimitris

Edité par CCSD ; American Association of Physicists in Medicine -

International audience. Partial volume effects (PVEs) are consequences of the limited spatial resolution in emission tomography leading to underestimation of uptake in tissues of size similar to the point spread function (PSF) of the scanner as well as activity spillover between adjacent structures. Among PVE correction methodologies, a voxel-wise mutual multiresolution analysis (MMA) was recently introduced. MMA is based on the extraction and transformation of high resolution details from an anatomical image (MR/CT) and their subsequent incorporation into a low-resolution PET image using wavelet decompositions. Although this method allows creating PVE corrected images, it is based on a 2D global correlation model, which may introduce artifacts in regions where no significant correlation exists between anatomical and functional details.

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