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Identification of ILK as a new partner of the ADAM12 disintegrin and metalloprotease in cell adhesion and survival.. Identification of ILK as a new partner of the ADAM12 disintegrin and metalloprotease in cell adhesion and survival.: ADAM12-ILK interaction

Archive ouverte | Leyme, Anthony | CCSD

International audience. Based on its shedding and binding activities, the disintegrin and metalloprotease 12 (ADAM12) has been implicated in cell signaling. Here we investigate the intracellular protein interaction ...

Protease profiling of liver fibrosis reveals the adam metallopeptidase with thrombospondin type 1 motif, 1 as a central activator of TGF-β

Archive ouverte | Bourd-Boittin, Katia | CCSD

International audience. During chronic liver disease, tissue remodeling leads to dramatic changes and accumulation of matrix components. Matrix metalloproteases and their inhibitors have been involved in the regulat...

The Disintegrin and Metalloprotease ADAM12 Is Associated with TGF-β-Induced Epithelial to Mesenchymal Transition

Archive ouverte | Ruff, Michaël | CCSD

International audience. The increased expression of the Disintegrin and Metalloprotease ADAM12 has been associated with human cancers, however its role remain unclear. We have previously reported that ADAM12 express...

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