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Cthrc1 is a negative regulator of myelination in Schwann cells

Archive ouverte | Apra, Caroline | CCSD

International audience. The analysis of the molecular mechanisms involved in the initial interaction between neurons and Schwann cells is a key issue in understanding the myelination process. We recently identified ...

Peripheral Myelin Maintenance Is a Dynamic Process Requiring Constant Krox20 Expression

Archive ouverte | Decker, Laurence | CCSD

International audience. Onset of myelination in Schwann cells is governed by several transcription factors, including Krox20/Egr2, and mutations affecting Krox20 result in various human hereditary peripheral neuropa...

CNS/PNS boundary transgression by central glia in the absence of Schwann cells or Krox20/Egr2 function.

Archive ouverte | Coulpier, Fanny | CCSD

International audience. CNS/PNS interfaces constitute cell boundaries, because they delimit territories with different neuronal and glial contents. Despite their potential interest in regenerative medicine, the mech...

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