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Role for interleukin-6 in COPD-related pulmonary hypertension.

Archive ouverte | Chaouat, Ari | CCSD

International audience. BACKGROUND: Pulmonary artery remodeling triggered by alveolar hypoxia is considered the main mechanism of pulmonary hypertension (PH) in COPD patients. We hypothesized that the risk for PH in...

Shortened telomeres in circulating leukocytes of patients with chronic obstructive pulmonary disease.. Shortened telomeres in circulating leukocytes of patients with chronic obstructive pulmonary disease.: telomere length in COPD

Archive ouverte | Savale, Laurent | CCSD

Ari Chaouat and Sylvie Bastuji-Garin equally contributed to the study. International audience. RATIONALE: Telomere length is considered a marker for biological aging. Chronic obstructive pulmonary disease (COPD) may...

Are Systemic Manifestations Ascribable to COPD in Smokers? A Structural Equation Modeling Approach

Archive ouverte | Boyer, Laurent | CCSD

International audience. Abstract Whether the systemic manifestations observed in Chronic Obstructive Pulmonary Disease (COPD) are ascribable to lung dysfunction or direct effects of smoking is in debate. Structural ...

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