YhbO protects cells against multiple stresses.

0 avis

YhbO protects cells against multiple stresses.

Archive ouverte

Abdallah, Jad | Caldas, Teresa | Kthiri, Fatoum | Kern, Renée | Richarme, Gilbert

Edité par CCSD ; American Society for Microbiology -

International audience. YhbO is a member of the DJ-1/ThiJ/Pfp1 superfamily, which includes chaperones, peptidases, and the Parkinson's disease protein DJ-1. A yhbO-disrupted mutant of Escherichia coli is highly sensitive to oxidative, thermal, UV, and pH stresses, and the putative nucleophilic cysteine C104 of YhbO is required for stress resistance. These results suggest that YhbO affects a central process in stress management.

Langue: en

Consulter en ligne

Consulter le document

Suggestions

Du même auteur

The thioredoxin homolog YbbN functions as a chaperone rather than as an oxidoreductase.

Archive ouverte | Kthiri, Fatoum | CCSD

International audience. Escherichia coli contains two thioredoxins, Trx1 and Trx2, and a thioredoxin-like protein, YbbN, which presents a strong homology in its N-terminal part with thioredoxins, and possesses a 20k...

Solubilization of protein aggregates by the acid-stress chaperones HDEA and HDEB.

Archive ouverte | Malki, Abderrahim | CCSD

International audience. The acid-stress chaperones HdeA and HdeB of Escherichia coli prevent the aggregation of periplasmic proteins at acidic pH. We show in this report that they also form mixed aggregates with pro...

YajL, the prokaryotic homolog of the Parkinsonism-associated protein DJ-1, protects cells against protein sulfenylation.

Archive ouverte | Gautier, Valérie | CCSD

International audience. YajL is the closest Escherichia coli homolog of the Parkinsonism-associated protein DJ-1, a multifunctional oxidative stress response protein whose biochemical function remains unclear. We re...

Chargement des enrichissements...