Suggestions

Du même auteur

The p21-activated kinase 3 implicated in mental retardation regulates spine morphogenesis through a Cdc42-dependent pathway.

Archive ouverte | Kreis, Patricia | CCSD

The p21-activated kinase 3 (PAK3) is one of the recently identified genes for which mutations lead to nonsyndromic mental retardation. PAK3 is implicated in dendritic spine morphogenesis and is a key regulator of synaptic function...

The four mammalian splice variants encoded by the p21-activated kinase 3 gene have different biological properties.

Archive ouverte | Kreis, Patricia | CCSD

The p21-activated kinases (PAK1), PAK2, and PAK3 are members of the PAK group I and share high sequence identity and common biochemical properties. PAK3 is specifically implicated in neuronal plasticity and also regulates cell cyc...

Alteration of Synaptic Network Dynamics by the Intellectual Disability Protein PAK3

Archive ouverte | Dubois, Aline | CCSD

International audience. Several gene mutations linked to intellectual disability in humans code for synaptic molecules implicated in small GTPase signaling. This is the case of the Rac/Cdc42 effector p21-activated k...

Chargement des enrichissements...