The inferferon-inducible gene, Ifi204, is transcriptionally activated in response to M-CSF and its expression favors macrophage differentiation in myeloid progenitor cells.

Archive ouverte | Dauffy, J. | CCSD

suppressor of cytokine signaling-1 (Socs1) interacts with the M-CSF receptor and negatively regulates its proliferation signal.

Archive ouverte | R.P., Bourette | CCSD

E2a/Pbx1 oncogene inhibits terminal differentiation but not myeloid potential of pro-T cells.

Archive ouverte | Bourette, R. P. | CCSD

E2a/Pbx1 is a fusion oncoprotein resulting from the t(1;19) translocation found in human pre-B acute lymphocytic leukemia and in a small number of acute T-lymphoid and myeloid leukemias. It was previously suggested that E2a/Pbx1 c...