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T-cadherin gene variants are associated with type 2 diabetes and the Fatty Liver Index in the French population

Archive ouverte | Nicolas, A. | CCSD

International audience. AimAdiponectin is an adipocyte-secreted protein associated with insulin sensitivity. T-cadherin is a receptor for high and medium molecular weight adiponectin. In GWAS, T-cadherin gene (CDH13...

Reassessment of the putative role of BLK-p.A71T loss-of-function mutation in MODY and type 2 diabetes

Archive ouverte | Bonnefond, A. | CCSD

International audience. MODY is believed to be caused by at least 13 different genes. Five rare mutations at the BLK locus, including only one non-synonymous p.A71T variant, were reported to segregate with diabetes ...

Relationship between renal capacity to reabsorb glucose and renal status in patients with diabetes

Archive ouverte | Matar, O. | CCSD

International audience. Aims: Interindividual variability in capacity to reabsorb glucose at the proximal renal tubule could contribute to risk of diabetic kidney disease. Our present study investigated, in patients...

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