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Loss of function of DJ-1 triggered by Parkinson's disease-associated mutation is due to proteolytic resistance to caspase-6.

Archive ouverte | Giaime, E. | CCSD

International audience. DJ-1 was recently identified as a gene product responsible for a subset of familial Parkinson's disease (PD). The mechanisms by which mutations in DJ-1 alter its function and account for PD-r...

Presenilin-dependent transcriptional control of the Ab-degrading enzyme neprilysin by intracellular domains of bAPP and APLP

Archive ouverte | Pardossi-Piquard, R. | CCSD

Presenilin-Dependent -Secretase-Mediated Control of p53-Associated Cell Death in Alzheimer's Disease

Archive ouverte | Alves da Costa, C. | CCSD

International audience

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