Pleiotropic effects of post-translational modifications on the fate of viral glycopeptides as cytotoxic T cell epitopes.

Archive ouverte | Hudrisier, Denis | CCSD

The fate of viral glycopeptides as cytotoxic T lymphocytes (CTL) epitopes is unclear. We have dissected the mechanisms of antigen presentation and CTL recognition of the peptide GP392-400 (WLVTNGSYL) from the lymphocytic choriomen...

Genetically encoded and post-translationnally modified forms of a major histocompatibility complex class-I restricted antigen bearing a glycosylation motif are independently processed and co-presented to cytotoxic T lymphocytes.

Archive ouverte | Hudrisier, Denis | CCSD

Molecular and functional dissection of the H-2Db-restricted subdominant cytotoxic T-cell response to lymphocytic choriomeningitis virus

Archive ouverte | Hudrisier, Denis | CCSD