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Archive ouverte | Abjean, Laurene | CCSD

International audience. Abstract Huntington’s disease is a fatal neurodegenerative disease characterized by striatal neurodegeneration, aggregation of mutant Huntingtin and the presence of reactive astrocytes. Astro...

Modulation of astrocyte reactivity improves functional deficits in mouse models of Alzheimer’s disease

Archive ouverte | Ceyzériat, Kelly | CCSD

International audience. Astrocyte reactivity and neuroinflammation are hallmarks of CNS pathological conditions such as Alzheimer’s disease. However, the specific role of reactive astrocytes is still debated. This c...

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Archive ouverte | Maté de Gérando, Anastasie | CCSD

International audience. Deposits of different abnormal forms of tau in neurons and astrocytes represent key anatomo-pathological features of tauopathies. Although tau protein is highly enriched in neurons and poorly...

Chargement des enrichissements...