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First Virtual International Congress on Cellular and Organismal Stress Responses, November 5–6, 2020

Archive ouverte | van Oosten-Hawle, Patricija | CCSD

International audience. Carolina at Charlotte, USA) organized a new virtual meeting format which took place on November 5-6, 2020. The goal of this congress was to provide an international platform for scientists to...

Protein quality control in the nucleolus safeguards recovery of epigenetic regulators after heat shock

Archive ouverte | Azkanaz, Maria | CCSD

International audience. Maintenance of epigenetic modifiers is of utmost importance to preserve the epigenome and consequently appropriate cellular functioning. Here, we analyzed Polycomb group protein (PcG) complex...

The S/T-Rich Motif in the DNAJB6 Chaperone Delays Polyglutamine Aggregation and the Onset of Disease in a Mouse Model.

Archive ouverte | Kakkar, Vaishali | CCSD

International audience. Expanded CAG repeats lead to debilitating neurodegenerative disorders characterized by aggregation of proteins with expanded polyglutamine (polyQ) tracts. The mechanism of aggregation involve...

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