Death and dying in hospitalized pediatric patients : a prospective multicenter, multinational study

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NICOLL, Jessica | DRYDEN-PALMER, Karen | FRNDOVA, Helena | GOTTESMAN, Ronald | GRAY, Martin | HUNT, Elizabeth A. | HUTCHISON, James S. | JOFFE, Ari R. | LACROIX, Jacques | MIDDAUGH, Kristen | NADKARNI, Vinay | SZADKOWSKI, Leah | TOMLINSON, George A. | WENSLEY, David | PARSHURAM, Chris S. | FARRELL, Catherine

Background: For hospitalized children admitted outside of a critical care unit, the location, mode of death, "do-not-resuscitate" order (DNR) use, and involvement of palliative care teams have not been described across high-income countries. Objective: To describe location of death, patient and terminal care plan characteristics of pediatric inpatient deaths inside and outside the pediatric intensive care unit (PICU). Design: Secondary analysis of inpatient deaths in the Evaluating Processes of Care and Outcomes of Children in Hospital (EPOCH) randomized controlled trial. Setting/Subjects: Twenty-one centers from Canada, Belgium, the United Kingdom, Ireland, Italy, the Netherlands, and New Zealand. Measurement: Descriptive statistics were used to compare patient and terminal care plan characteristics. A multivariable generalized estimating equation examined if palliative care consult during hospital admission was associated with location of death. Results: A total of 365 of 144,539 patients enrolled in EPOCH died; 219 (60%) died in PICU and 143 (40%) died on another inpatient unit. Compared with other inpatient wards, patients who died in PICU were less likely to be expected to die, have a DNR or palliative care consult. Hospital palliative care consultation was more common in older children and independently associated with a lower adjusted odds (95% confidence interval) of dying in PICU [0.59 (0.52-0.68)]. Conclusion: Most pediatric inpatient deaths occur in PICU where patients were less likely to have a DNR or palliative care consult. Palliative care consultation could be better integrated into end-of-life care for younger children and those dying in PICU.

http://dx.doi.org/10.1089/jpm.2021.0205

Voir la revue «JOURNAL OF PALLIATIVE MEDICINE, 25»

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