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Risk of rabies transmission and adverse effects of postexposure prophylaxis in health care workers exposed to a fatal case of human rabies.

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Mahamat, Andre | Meynard, Jean-Baptiste | Djossou, Félix | Dussart, Philippe | Demar, Magalie Pierre | Fontanella, Jean-Michel | Hommel, Didier | Flamand, Claude | Bourhy, Hervé | Spiegel, Andre

Edité par CCSD ; Elsevier -

Presented in part as an oral communication at the 10th Journées Nationales d’Infectiologie, Marseille, France, June 10-12, 2009.. International audience. On May 27, 2008, a patient died from rabies at the Cayenne Hospital in French Guiana. Postexposure prophylaxis vaccination was implemented for all health care workers exposed to this patient. Examining the management of such a rare risk reveals important factors in the education of personnel who may have contact with a patient with rabies, to permit appropriate risk assessment and reduce unnecessary postexposure prophylaxis, taking into account the risks and costs of adverse events.

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