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Ensembling Unets for rare chromosal aberration detection in metaphase images, uncertainty quantification, and ionizing radiation dose estimation

Archive ouverte | Deschemps, Antonin | CCSD

In biological dosimetry a radiation dose is estimated using the average number of chromosomal aberrations per peripheral blood lymphocytes. This analysis is still manually performed on 2D metaphase images depicting the 23 pairs of...

Characterizing the DNA damage signaling response of cell populations exposed to mixed radiation fields from monoenergetic neutrons

Archive ouverte | Gonon, Geraldine | CCSD

International audience. The most prevalent type of ionizing radiation to which humans are exposed consists of mixed ionizing radiation fields. While exposure to a specific type of radiation (X and γ rays, α particle...

RENEB Inter-Laboratory Comparison 2021: The FISH-Based Translocation Assay

Archive ouverte | Barquinero, J-F | CCSD

International audience. Translocation analysis using fluorescence in situ hybridization (FISH) is the method of choice for dose assessment in case of chronic or past exposures to ionizing radiation. Although it is a...

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