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Platelets and vascular integrity: how platelets prevent bleeding in inflammation

Archive ouverte | Ho-Tin-Noé, Benoit | CCSD

International audience. Platelets play a central role in primary hemostasis by forming aggregates that plug holes in injured vessels. Half a century ago, detailed studies of the microvasculature by electron microsco...

Thrombus Composition and Thrombolysis Resistance in Stroke

Archive ouverte | Ho Tin Noé, Benoit | CCSD

International audience. A State of the Art lecture titled "Thrombus Composition and Thrombolysis Resistance in Stroke" was presented at the ISTH Congress in 2022. Intravenous thrombolysis (IVT) remains the only phar...

The reversed passive Arthus reaction as a model for investigating the mechanisms of inflammation-associated hemostasis

Archive ouverte | Le Chapelain, Ophélie | CCSD

International audience. In recent years, accumulating evidence has indicated that platelets continuously repair vascular damage at sites of inflammation and/or infection. Studies in mouse models of inflammation have...

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