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In Vitro and Ex Vivo Evaluation of Smart Infra-Red Fluorescent Caspase-3 Probes for Molecular Imaging of Cardiovascular Apoptosis

Archive ouverte | Debunne, Manuelle | CCSD

International audience. PURPOSE:The aim of this paper is to develop new optical bioprobes for the imaging of apoptosis.PROCEDURE:We developed quenched near-infrared probes which become fluorescent upon cleavage by c...

Arteriogenic Therapy by Intramyocardial Sustained Delivery of a Novel Growth Factor Combination Prevents Chronic Heart Failure

Archive ouverte | Banquet, Sébastien | CCSD

Comment in "Prevention and recovery of hibernating myocardium by microvascular repair. [Circulation. 2011]". International audience. BACKGROUND:Therapeutic angiogenesis is a promising approach for the treatment of c...

Heart Rate Reduction Induced by the If Current Inhibitor Ivabradine Improves Diastolic Function and Attenuates Cardiac Tissue Hypoxia

Archive ouverte | Fang, Yuehua | CCSD

International audience. Aims: Enhanced heart rate (HR) is a compensatory mechanism in chronic heart failure (CHF), preserving cardiac output, but at the cost of increased left ventricular (LV) oxygen consumption and...

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