Iterative fecal microbiota transplantations for eradicating digestive colonization with carbapenemase-producing Enterobacteriaceae: is it worth it?

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Mahieu, Rafael | Cassisa, Viviane | Sanderink, Diane | Chenouard, Rachel | Pailhoriès, Hélène | Kempf, Marie | Dubée, Vincent | Eveillard, Matthieu

Edité par CCSD ; University of Chicago Press -

International audience. Carbapenemase-producing Enterobacteriaceae (CPE) have emerged as a major source of bacterial resistance and their dissemination is a serious public health threat.1 It has also been demonstrated that those bacteria could disseminate outside the hospital setting. A large study including 34 hospitals in Spain demonstrated that a significant proportion of patients identified as colonized or infected with CPE during hospitalization probably acquired this multi-resistant organism in a nursing home during the period preceding their hospital admission.2 In addition, a recent review of the literature demonstrated that according to US-based studies, the percentage of CPE isolates that could be associated with the community ranged from 5.6 to 10.8%.3

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