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Dual control of Kinesin-1 recruitment to microtubules by Ensconsin in Drosophila neuroblasts and oocytes

Archive ouverte | Métivier, Mathieu | CCSD

International audience. Drosophila Ensconsin (also known as MAP7) controls spindle length, centrosome separation in brain neuroblasts (NBs) and asymmetric transport in oocytes. The control of spindle length by Ensco...

The spindle assembly checkpoint and the spatial activation of Polo kinase determine the duration of cell division and prevent tumor formation

Archive ouverte | Gallaud, Emmanuel | CCSD

International audience. The maintenance of a restricted pool of asymmetrically dividing stem cells is essential for tissue homeostasis. This process requires the control of mitotic progression that ensures the accur...

Aurora kinases promote mitotic progression and asymmetric cell division through activation of Polo kinase

Archive ouverte | Gallaud, Emmanuel | CCSD

Organ development and integrity requires the maintenance of a defined and restricted pool of dividing stem cells. This process requires the coupling of mitosis progression to the establishment of stem cells polarization and spindl...

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