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AGuIX® from bench to bedside—Transfer of an ultrasmall theranostic gadolinium-based nanoparticle to clinical medicine

Archive ouverte | Lux, François | CCSD

International audience. AGuIX® are sub-5 nm nanoparticles made of a polysiloxane matrix and gadolinium chelates. This nanoparticle has been recently accepted in clinical trials in association with radiotherapy. This...

Treatment of multiple brain metastases using gadolinium nanoparticles and radiotherapy: NANO-RAD, a phase I study protocol

Archive ouverte | Verry, Camille | CCSD

International audience. INTRODUCTION:Occurrence of multiple brain metastases is a critical evolution of many cancers with significant neurological and overall survival consequences, despite new targeted therapy and ...

The use of theranostic gadolinium-based nanoprobes to improve radiotherapy efficacy

Archive ouverte | Sancey, Lucie | CCSD

International audience. A new efficient type of gadolinium-based theranostic agent (AGuIX) has recently been developed for magnetic resonance imaging (MRI)-guided radiotherapy. These new particles consist of a polys...

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