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Androgen receptor-mediated transcriptional repression targets cell plasticity in prostate cancer

Archive ouverte | Erdmann, Eva | CCSD

Androgen receptor (AR) signaling remains the key therapeutic target in the management of hormone-naive advanced prostate cancer (PCa) and castration-resistant PCa (CRPC). Recently, landmark molecular features have been reported fo...

Dual effects of constitutively active androgen receptor and full-length androgen receptor for N-cadherin regulation in prostate cancer

Archive ouverte | Cottard, Felicie | CCSD

Constitutively active androgen receptor (AR) variants have been involved in the expression of mesenchymal markers such as N-cadherin in prostate cancer (PCa). However, the underlying molecular mechanisms remain elusive. It remains...

COVID -19 in Patients with Cancer: A Retrospective Study of 212 Cases from a French SARS-CoV -2 Cluster During the First Wave of the COVID -19 Pandemic

Archive ouverte | Martin, Sophie | CCSD

International audience. Abstract We describe a large series of patients with solid tumors in an early COVID-19 cluster in the eastern part of France. From February to May 2020, this multicenter retrospective study e...

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