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Archive ouverte | Garcia, Cedric | CCSD

International audience. Background: Availability of multichannel cytometers and specific commercial antibodies makes flow cytometry a new option to simultaneously assess multiple intracellular platelet signaling pat...

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Archive ouverte | Garcia, Cédric | CCSD

International audience. Introduction: The platelet P2Y12 receptor (P2Y12-R) for adenosine diphosphate (ADP) plays a crucial role in platelet activation and thus constitutes one of the major drug targets to inhibit p...

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Archive ouverte | Ribes, Agnès | CCSD

International audience. BackgroundPurinergic P2Y1 and P2Y12 receptors (P2Y1-R and P2Y12-R) are G protein-coupled receptors (GPCR) activated by adenosine diphosphate (ADP) to mediate platelet activation, thereby play...

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