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Glypican-3 is a key tuner of the Hedgehog pathway in COPD

Archive ouverte | Petit, Laure, M G | CCSD

International audience. Hedgehog (HH) pathway is involved in pulmonary development and lung homeostasis. It orchestrates airway epithelial cell (AEC) differentiation and contributes to respiratory pathogenesis.The c...

The Nicotinic Receptor Polymorphism rs16969968 Is Associated with Airway Remodeling and Inflammatory Dysregulation in COPD Patients

Archive ouverte | Saber Cherif, Lynda | CCSD

International audience. Genome-wide association studies unveiled the associations between the single nucleotide polymorphism rs16969968 of CHRNA5, encoding the nicotinic acetylcholine receptor alpha5 subunit (α5SNP)...

Airway epithelial TSLP production is increased in COPD patients

Archive ouverte | Saber Cherif, Lynda | CCSD

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