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Modeling the Simultaneous Dynamics of Proteins in Blood Plasma and the Cerebrospinal Fluid in Human In Vivo

Archive ouverte | Giroux, Pierre | CCSD

International audience. Introduction (Words remaining 120)Protein turnover analysis provides crucial insights into disease-related alterations in synthesis, degradation, and transport dynamics. Here, we present a no...

IN VIVO LARGE SCALE MAPPING OF PROTEIN TURNOVER IN THE HUMAN CEREBROSPINAL FLUID

Archive ouverte | Lehmann, Sylvain | CCSD

International audience. The extraction of accurate physiological parameters from clinical samples provides a unique perspective to understand disease etiology and evolution, including under therapy. We introduce a n...

Enabling Population Protein Dynamics Through Bayesian Modeling

Archive ouverte | Lehmann, Sylvain | CCSD

International audience. Abstract Motivation The knowledge of protein dynamics, or turnover, in patients provides invaluable information related to certain diseases, drug efficacy, or biological processes. A great co...

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