Does DHA open TREK-1 channels or is it NEO-PUFAs?

Archive ouverte

Bertaud, Anaïs | Salmeron, Fanny | Oger, Camille | Galano, Jean-Marie | Vigor, Claire | Jopling, Chris | Durand, Thierry | Le Guennec, Jean-Yves | Moha Ou Maati, Hamid | Demion, Marie

Edité par CCSD -

International audience. In 2015 more than 17 millions of deaths inwestern world were due to cardiovascular diseases of which 25% were accounted to sudden cardiac death (SCD). Only afew part of SCD is prevented by cardiac defibrillator implan-tation and anti-arrhythmic treatment.

Consulter en ligne

Suggestions

Du même auteur

Impact of DHA on the cardiac function and regeneration mechanisms in zebrafish

Archive ouverte | Salmeron, Fanny | CCSD

International audience. Introduction: Cardiovascular diseases are the leading cause of death worldwide, accounting for 31% of all deaths globally. Pharmacological treatments are used to treat myocardial infarction, ...

From MS/MS library implementation to molecular networks: Exploring oxylipin diversity with NEO-MSMS

Archive ouverte | Elloumi, Anis | CCSD

International audience. Oxylipins, small polar molecules derived from the peroxidation of polyunsaturated fatty acids (PUFAs), serve as biomarkers for many diseases and play crucial roles in human physiology and inf...

Activation of hTREK-1 by polyunsaturated fatty acids involves direct interaction

Archive ouverte | Bechard, Emilie | CCSD

International audience. TREK-1 is a mechanosensitive channel activated by polyunsaturated fatty acids (PUFAs). Its activation is supposed to be linked to changes in membrane tension following PUFAs insertion. Here, ...

Chargement des enrichissements...