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Automated workflows for 13 C-Fluxomics: Increasing throughput and accessibility of 13 C-Fluxomics
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Edité par CCSD -
International audience. The goal of isotope-based fluxomics approaches is to quantify metabolic fluxes in living organisms. 13C-fluxomics provides a detailed phenotypic description of the actual metabolic state of studied organisms. To achieve this, a combination of several experimental and computational steps is required. However, the complexity of the computational steps, coupled with the need to select the right software while manually ensuring data interoperability, makes the process error-prone, time-consuming, and hard to reproduce effectively. The objective of this project is to overcome these limitations by providing a flexible, reproducible, user-friendly, and high-throughput 13C-fluxomics workflow that integrates the tools needed for flux calculation.
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