ADVANCING ALZHEIMER’S DISEASE TREATMENT: LESSONS FROM CTAD 2018

Archive ouverte

Vellas, B. | Bain, L.J. | Touchon, J. | Aisen, P.S.

Edité par CCSD ; SERDI éd -

International audience. The 2018 Clinical Trials on Alzheimer’s Disease (CTAD) conference showcased recent successes and failures in trials of Alzheimer’s disease treatments. More importantly, the conference provided opportunities for investigators to share what they have learned from those studies with the goal of designing future trials with a greater likelihood of success. Data from studies of novel and non-amyloid treatment approaches were also shared, including neuroprotective and regenerative strategies and those that target neuroinflammation and synaptic function. New tools to improve the efficiency and productivity of clinical trials were described, including biomarkers and machine learning algorithms for predictive modeling.

Consulter en ligne

Suggestions

Du même auteur

Platform Trials to Expedite Drug Development in Alzheimer’s Disease. Platform Trials to Expedite Drug Development in Alzheimer’s Disease: A Report from the EU/US CTAD Task Force

Archive ouverte | Aisen, P.S. | CCSD

International audience. A diverse range of platforms has been established to increase the efficiency and speed of clinical trials for Alzheimer’s disease (AD). These platforms enable parallel assessment of multiple ...

Rapid cognitive decline in Alzheimer's disease. Consensus paper.

Archive ouverte | Soto, M. E. | CCSD

International audience. The rate of cognitive decline in Alzheimer's disease (AD) varies considerably between individuals, with some subjects showing substantial deterioration and others showing little or no change ...

Registries and Cohorts to Accelerate Early Phase Alzheimer's Trials. A Report from the E.U./U.S. Clinical Trials in Alzheimer's Disease Task Force.

Archive ouverte | Aisen, P. | CCSD

International audience. The EU/US/CTAD Task Force, an international collaboration of AD investigators from industry and academia, met in Barcelona, Spain, on November 4th, 2015, to explore existing and planned patie...

Chargement des enrichissements...