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Implantation of engineered human microvasculature to study human infectious diseases in mouse models

Archive ouverte | Schönherr-Hellec, Sophia | CCSD

International audience. Animal models for studying human pathogens are crucially lacking. We describe the implantation in mice of engineered human mature microvasculature consisting of endothelial and perivascular c...

Implantation of engineered human microvasculature to study human infectious diseases in mouse models

Archive ouverte | Schönherr-Hellec, Sophia | CCSD

International audience. Animal models for studying human pathogens are crucially lacking. We describe the implantation in mice of engineered human mature microvasculature consisting of endothelial and perivascular c...

The minor pilin PilV provides a conserved adhesion site throughout the antigenically variable meningococcal type IV pilus

Archive ouverte | Barnier, Jean-Philippe | CCSD

International audience. Neisseria meningitidis utilizes type IV pili (T4P) to adhere to and colonize host endothelial cells, a process at the heart of meningococcal invasive diseases leading to meningitis and sepsis...

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