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Is minimally invasive surgical approach a reasonable option in apparent early stage epithelial ovarian cancer restaging? Results from a multicentric retrospective study
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Edité par CCSD ; WB Saunders -
International audience. To perform surgical staging of early stage ovarian cancer (EOC), conventional laparoscopy (LS) androbot-assisted laparoscopy (RLS) appear to be reliable procedures compared to open surgery. But oncologicalsresults with long-term follow up are limited in the literature. The objective of this study is to evaluate the surgicaland long-term survival for patients managed by minimally invasive surgery (MIS).Materials and methods: We conducted a multicentric retrospective study in 6 institutions. All patients referred forepithelial EOC (apparent stage I-IIa) managed with LS and RLS were involved.Results: From December 2008 to December 2017, 140 patients were included (109 in LS group and 31 in RLSgroup). A total of 27 (19.2 %) patients were upstaged to an advanced ovarian cancer (FIGO stage > IIA), and 73% of patients received chemotherapy. Mean operative time was 265,8 ± 88,4 min and significantly longer in RLSgroup (LS = 254,5 ± 86,8; RLS = 305,6 ± 85,5; p = 0,008). Rate of severe post-operative complications (grade3) was 5,7 %. Thirteen conversion to laparotomy occurred, including one per-operative hemorrhaege. After amean follow-up of 60,7 months, 29 (20.7 %) patients recurred, with a time to recurrence was >24 months in 51,7% of cases. Overall survival (OS) was 88.6 % and disease-free survival (DFS) was 79.3 %. Oncologic outcomeswere similar between LS and RLS group (OS: p = 0,504 and DFS: p = 0,213).Conclusion: Surgical staging of EOC by LS or RLS approach has long-term equivalent surgical and oncologicalapproach. These results seem to be equivalent to open surgery according to literature review
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