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Radiological evaluation of newly diagnosed non-brainstem pediatric High-Grade Glioma in the HERBY Phase II trial. Exploiter les dépendances non-oncogéniques afin d’identifier de nouvelles cibles thérapeutiques dans les cancers pédiatriques

Archive ouverte | Rodriguez Gutierrez, Daniel | CCSD

International audience. Abstract Purpose: The HERBY trial evaluated the benefit of the addition of the antiangiogenic agent Bevacizumab (BEV) to radiotherapy/temozolomide (RT/TMZ) in pediatric patients with newly di...

Phase II, Open-Label, Randomized, Multicenter Trial (HERBY) of Bevacizumab in Pediatric Patients With Newly Diagnosed High-Grade Glioma

Archive ouverte | Grill, Jacques | CCSD

International audience. Purpose Bevacizumab (BEV) is approved in more than 60 countries for use in adults with recurrent glioblastoma. We evaluated the addition of BEV to radiotherapy plus temozolomide (RT+TMZ) in p...

Molecular, Pathological, Radiological, and Immune Profiling of Non-brainstem Pediatric High-Grade Glioma from the HERBY Phase II Randomized Trial

Archive ouverte | Mackay, Alan | CCSD

International audience. The HERBY trial was a phase II open-label, randomized, multicenter trial evaluating bevacizumab (BEV) in addition to temozolomide/radiotherapy in patients with newly diagnosed non-brainstem h...

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