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Natural nanocarriers-based mTHPC for the photodynamic therapy

Archive ouverte | Millard, Marie | CCSD

International audience. meta-Tetrakis(3-hydroxylphenyl)chlorin (mTHPC, Foscan®) is one of the most potent clinically approved photosensitizer (PS) for photodynamic therapy (PDT) and is characterized by high absorpti...

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Archive ouverte | Millard, Marie | CCSD

International audience. Extracellular vesicles (EVs), derived from the cell, display a phospholipid bilayer membrane that protects the cargo molecules from degradation and contributes to increasing their stability i...

mTHPC-loaded extracellular vesicles outperform liposomal and free mTHPC formulations by an increased stability, drug delivery efficiency and cytotoxic effect in tridimensional model of tumors

Archive ouverte | Millard, Marie | CCSD

International audience. Efficient photodynamic therapy with meta-tetra(hydroxyphenyl)chlorine requires the application of specific nanoformulations. mTHPC liposomal formulation (Foslip®) demonstrated favorable pharm...

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