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Rebleeding and mortality risk are increased by ACLF but reduced by pre-emptive TIPS

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Trebicka, Jonel | Gu, Wenyi | Ibáñez-Samaniego, Luis | Hernández-Gea, Virginia | Pitarch, Carla | Garcia, Elisabet | Procopet, Bogdan | Giráldez, Álvaro | Amitrano, Lucio | Villanueva, Candid | Thabut, Dominique | Silva-Junior, Gilberto | Martinez, Javier | Genescà, Joan | Bureau, Cristophe | Llop, Elba | Laleman, Wim | Palazon, Jose Maria | Castellote, Jose | Rodrigues, Susanag | Gluud, Liselotte | Ferreira, Carlos Noronha | Barcelo, Rafael | Cañete, Nuria | Rodríguez, Manuel | Ferlitsch, Arnulf | Mundi, Jose Luis | Gronbaek, Henning | Hernández-Guerra, Manuel | Sassatelli, Romano | Dell'Era, Alessandra | Senzolo, Marco | Abraldes, Juan, G | Romero-Gómez, Manuel | Zipprich, Alexander | Casas, Meritxell | Masnou, Helena | Primignani, Massimo | Weiss, Emmanuel | Catalina, Maria-Vega | Erasmus, Hans-Peter | Uschner, Frank Erhard | Schulz, Martin | Brol, Maximilian, J | Praktiknjo, Michael | Chang, Johannes | Krag, Aleksander | Nevens, Frederik | Calleja, Jose Luis | Robic, Marie Angèle | Conejo, Irene | Albillos, Agustin | Rudler, Marika | Alvarado, Edilmar | Guardascione, Maria Anna | Tantau, Marcel | Bosch, Jaime | Torres, Ferran | Pavesi, Marco | Garcia-Pagán, Juan Carlos | Jansen, Christian | Bañares, Rafael

Edité par CCSD ; Elsevier -

International audience. Respiration Coagulation Brain Liver Circulation Kidney Acute-on-chronic liver failure (ACLF) AVB + ACLF High rebleeding rate (25.2%) in 42 days High mortality rate (51.0%) in 42 days Pre-emptive TIPS in AVB + ACLF Low rebleeding rate (4.5%) in 42 days Low mortality rate (13.6%) in 42 days Pre-emptive TIPS Acute Variceal Bleeding (AVB) Highlights Variceal bleeding is frequently associated with ACLF in cirrhosis. ACLF is independently associated with rebleeding and mortality. Patients with variceal bleeding and ACLF can benefit from a preemptive (early) TIPS.

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