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Cyclic imine toxins survey in coastal european shellfish samples: Bioaccumulation and mode of action of 28-O-palmitoyl ester of pinnatoxin-G. first report of portimine-A bioaccumulation

Archive ouverte | Aráoz, Rómulo | CCSD

International audience. Cyclic imine toxins exhibit fast acting neurotoxicity and lethality by respiratory arrest in mice explained by their potent antagonistic activity against muscular nicotinic acetylcholine rece...

Pinnatoxin G is responsible for atypical toxicity in mussels (Mytilus galloprovincialis) and clams (Venerupis decussata) from Ingril, a French Mediterranean lagoon.

Archive ouverte | Hess, Philipp | CCSD

International audience. Following a review of official control data on shellfish in France, Ingril Lagoon had been identified as a site where positive mouse bioassays for lipophilic toxins had been repeatedly observ...

Cyclic imine toxins: From shellfish poisoning to neuroscience: The case of acyl derivatives

Archive ouverte | Aráoz, Rómulo | CCSD

International audience. Pinnatoxins belong to an emerging class of phycotoxins of the cyclic imine group. Detailed studies of their biological effects have been impeded for a long time due to unavailability of both ...

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