Consulter en ligne

Suggestions

Du même auteur

STIM2 variants regulate Orai1/TRPC1/TRPC4-mediated store-operated Ca2+ entry and mitochondrial Ca2+ homeostasis in cardiomyocytes

Archive ouverte | Luo, Rui | CCSD

International audience. The stromal interaction molecules (STIMs) are the sarcoplasmic reticulum (SR) Ca2+ sensors that trigger store-operated Ca2+ entry (SOCE) in a variety of cell types. While STIM1 isoform has be...

The SOCE Machinery: An Unbalanced Knowledge between Left and Right Ventricular Pathophysiology

Archive ouverte | Sabourin, Jessica | CCSD

International audience. Right ventricular failure (RVF) is the most important prognostic factor for morbidity and mortality in pulmonary arterial hypertension (PAH) or pulmonary hypertension (PH) caused by left hear...

Orai1 Channel Inhibition Preserves Left Ventricular Systolic Function and Normal Ca 2+ Handling After Pressure Overload

Archive ouverte | Bartoli, Fiona | CCSD

International audience. Background: Orai1 is a critical ion channel subunit, best recognized as a mediator of store-operated Ca 2+ entry (SOCE) in nonexcitable cells. SOCE has recently emerged as a key contributor o...

Chargement des enrichissements...