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Patisiran Treatment in Patients with Transthyretin Cardiac Amyloidosis

Archive ouverte | Maurer, Mathew | CCSD

International audience. Background: Transthyretin amyloidosis, also called ATTR amyloidosis, is associated with accumulation of ATTR amyloid deposits in the heart and commonly manifests as progressive cardiomyopathy...

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Archive ouverte | Delbarre, Marc‐antoine | CCSD

International audience. Background The frequent association between transthyretin wild‐type (TTRwt) cardiac amyloidosis (CA) and aortic stenosis (AS) suggests a bidirectional relationship: TTRwt‐CA could induce AS a...

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Archive ouverte | Bézard, Mélanie | CCSD

International audience. Hereditary (ATTRv) and wild-type (ATTRwt) transthyretin amyloidosis are severe and fatal systemic diseases, characterised by amyloid fibrillar accumulation principally in the heart or periphe...

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