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Direct action of the Nodal-related signal Cyclops in induction of sonic hedgehog in the ventral midline of the CNS

Archive ouverte | Müller, Ferenc | CCSD

International audience. ABSTRACT The secreted molecule Sonic hedgehog (Shh) is crucial for floor plate and ventral brain development in amniote embryos. In zebrafish, mutations in cyclops (cyc), a gene that encodes ...

Cooperation of sonic hedgehog enhancers in midline expression.

Archive ouverte | Ertzer, Raymond | CCSD

International audience. In zebrafish, as in other vertebrates, the secreted signalling molecule Sonic hedgehog (Shh) is expressed in organiser regions such as the embryonic midline and the zona limitans intrathalami...

Cyclops-independent floor plate differentiation in zebrafish embryos

Archive ouverte | Albert, Stéphanie | CCSD

International audience. In zebrafish, development of the ventral neural tube depends on the Nodal-related signal Cyclops (Cyc). One-day-old cyc mutant embryos lack the medial floor plate (MFP). We show here that cel...

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