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Hypoxia inducible factors regulate hepatitis B virus replication by activating the basal core promoter

Archive ouverte | Wing, Peter | CCSD

PMC8214165. BACKGROUND & AIMS: Hypoxia inducible factors (HIFs) are a hallmark of inflammation and are key regulators of hepatic immunity and metabolism, yet their role in HBV replication is poorly defined. HBV repl...

Circadian control of hepatitis B virus replication

Archive ouverte | Zhuang, Xiaodong | CCSD

PMC7955118. Chronic hepatitis B virus (HBV) infection is a major cause of liver disease and cancer worldwide for which there are no curative therapies. The major challenge in curing infection is eradicating or silen...

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Archive ouverte | Magri, Andrea | CCSD

International audience. Chronic hepatitis B virus (HBV) infection is a global health problem that presents as a spectrum of liver disease, reflecting an interplay between the virus and the host immune system. HBV ge...

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