Cortical folding difference between patients with early-onset and patients with intermediate-onset bipolar disorder

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Penttilä, Jani | Cachia, Arnaud | Martinot, Jean-Luc | Ringuenet, Damien | Wessa, Michèle | Houenou, Josselin | Galinowski, André | Bellivier, Frank | Gallarda, Thierry | Duchesnay, Edouard | Artiges, Eric | Leboyer, Marion | Olié, Jean-Pierre | Mangin, Jean-François | Paillère-Martinot, Marie-Laure

Edité par CCSD ; Wiley -

International audience. Cerebral abnormalities have been detected in patients with bipolar disorder (BD). In comparison to BD with a later onset, early-onset BD has been found to have a poorer outcome. However, it is yet unknown whether neuroanatomical abnormalities differ between age-at-onset subgroups of the illness. We searched for cortical folding differences between early-onset (before 25 years) and intermediate-onset (between 25 and 45 years) BD patients.

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