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Thrombin activation of protein C requires prior processing by a liver proprotein convertase.

Archive ouverte | Essalmani, Rachid | CCSD

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Disruption of the expression of the proprotein convertase PC7 reduces BDNF production and affects learning and memory in mice

Archive ouverte | Wetsel, William | CCSD

International audience. Significance The 7-membered proprotein convertase (PC) family of basic amino acid-specific proteases is implicated in the cleavage-activation of secretory precursor proteins. Although the in ...

Amyloid Precursor-like Protein 2 and Sortilin Do Not Regulate the PCSK9 Convertase-mediated Low Density Lipoprotein Receptor Degradation but Interact with Each Other

Archive ouverte | Butkinaree, Chutikarn | CCSD

International audience. Amyloid precursor-like protein 2 (APLP2) and sortilin were reported to individually bind the proprotein convertase subtilisin/kexin type 9 (PCSK9) and regulate its activity on the low-density...

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