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Nuclear Factor Erythroid 2-Related Factor 2 Drives Podocyte-Specific Expression of Peroxisome Proliferator-Activated Receptor γ Essential for Resistance to Crescentic GN

Archive ouverte | Henique, Carole | CCSD

International audience. Necrotizing and crescentic rapidly progressive GN (RPGN) is a life-threatening syndrome characterized by a rapid loss of renal function. Evidence suggests that podocyte expression of the tran...

The tetraspanin CD9 controls migration and proliferation of parietal epithelial cells and glomerular disease progression

Archive ouverte | Lazareth, Hélène | CCSD

These authors contributed equally : Hélène Lazareth, Carole Henique, Olivia Lenoir, Victor G. Puelles.These authors jointly supervised this work : François Le Naour, Eric Rubinstein, Claude Boucheix, Antigoni Alexandrou, Marcus J....

Genetic and pharmacological inhibition of microRNA-92a maintains podocyte cell cycle quiescence and limits crescentic glomerulonephritis

Archive ouverte | Henique, Carole | CCSD

International audience. Crescentic rapidly progressive glomerulonephritis (RPGN) represents the most aggressive form of acquired glomerular disease. While most therapeutic approaches involve potentially toxic immuno...

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