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Real-time mechanical characterization of DNA degradation under therapeutic X-rays and its theoretical modeling

Archive ouverte | Perret, Grégoire | CCSD

International audience. Abstract The killing of tumor cells by ionizing radiation beams in cancer radiotherapy is currently based on a rather empirical understanding of the basic mechanisms and effectiveness of DNA ...

A rapid and practical technique for real-time monitoring of biomolecular interactions using mechanical responses of macromolecules

Archive ouverte | Tarhan, Mehmet | CCSD

International audience. Monitoring biological reactions using the mechanical response of macromolecules is an alternative approach to immunoassays for providing real-time information about the underlying molecular m...

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Archive ouverte | Tauran, Yannick | CCSD

International audience. The couple Calix[4]arene-1,3-O-diphosphorous acid (C4diP) and zinc ions (Zn 2+) acts as a synergistic DNA binder. Silicon NanoTweezer (SNT) measurements show an increase in the mechanical sti...

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