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Cerebrospinal Fluid and Plasma Biomarkers do not Differ in the Presenile and Late-Onset Behavioral Variants of Frontotemporal Dementia

Archive ouverte | Menjot de Champfleur, Nicolas | CCSD

International audience. : Background:Memory troubles and hippocampal atrophy are considered more frequent and focal atrophy less severe in late-onset (>65 years) than in presenile behavioral variant frontotemporal d...

Penetrance estimation of Alzheimer disease in SORL1 loss-of-function variant carriers using a family-based strategy and stratification by APOE genotypes

Archive ouverte | Schramm, Catherine | CCSD

International audience. Abstract Background Alzheimer disease (AD) is a common complex disorder with a high genetic component. Loss-of-function (LoF) SORL1 variants are one of the strongest AD genetic risk factors. ...

Absence of Relationship Between Self-Reported Sleep Measures and Amyloid Load in Elderly Subjects

Archive ouverte | Gabelle, Audrey | CCSD

International audience. Objective: To determine the relationships between self-reported sleep profile and cortical amyloid load in elderly subjects without dementia. Methods: This cross-sectional study included 143 ...

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